President Obama and Hillary Clinton also congratulated the team.
It was a celebration 108 years in the making as the Chicago Cubs beat the Cleveland Indians, 8-7, in the 10th inning to capture their first world championship since 1908.
Champagne mixed with tears in the joyous Cubs locker room.
Bill Murray, who has been at every game of the series, joined the celebration at Progressive Field in Cleveland.
The Ghostbusters actor grabbed a Fox Sports mic and interviewed Cubs general manager Theo Epstein.
Murray asked Epstein: “Is there anybody you want to say hello to that you have thought about lately?”
Epstein then said: “Yeah, you,” as he opened a bottle of champagne and sprayed the actor with bubbly.
Murray than returned the favor by pouring a bottle on Epstein's head.
“My mother thanks you, my father thanks you, my sisters thank you and my brothers thank you,” the Life Aquatic actor told Epstein.
Following the win, President Obama, a lifelong Chicago White Sox fan, congratulated the team and invited them to the White House before he leaves office in January.
It happened: @Cubs win World Series. That's change even this South Sider can believe in. Want to come to the White House before I leave?
— President Obama (@POTUS) November 3, 2016
Pearl Jam’s Eddie Vedder, who sang during the Seventh-Inning Stretch at Wrigley Field in previous World Series games, celebrated with the team on the field.
He told Chicago’s WGN-TV that the whole series and team have been “an inspiration.”
About 300 miles away from Cleveland, Cubs fans packed the bars and the streets in Chicago's Wrigleyville section.
The city erupted in pure elation as fans, most of whom have waited their whole lives for that moment, took to the streets.
Hillary Clinton, a lifelong Cubs fan, watched the game on an iPad while on the campaign trail in Arizona.
Following the victory, she tweeted:
They did it! 108 years later and the drought is finally over. Way to make history, @Cubs. #FlyTheW -H
— Hillary Clinton (@HillaryClinton) November 3, 2016
The Cubs arrived home in Chicago Thursday morning, holding the trophy high after winning one of the most heart-pounding games in World Series history.
LeBron James, whose Cleveland Cavaliers brought the city their first championship earlier in the year and came back from a 3-1 game deficit just like the Cubs, was at the game with teammate J.R. Smith.
Read: For the Love of Cubs: Bill Murray Makes Fan's Night as He Treats Her to World Series Ticket
James sent a message to Indians fans following the loss saying: “Just want to congratulate the Indians on an unbelievable season. You guys did something that nobody would ever think you guys could do, and we’re very proud of you. The whole Cavs organization, all the fans, the whole city of Cleveland—we’re all proud of you guys. You guys got nothing to hang your heads low about. Use this as inspiration to get ready for next year."
He also congratulated the Cubs: “The first one in, I think it’s 100-plus years. Magical season for y’all. You guys were the best team in baseball all year, and you guys showed why."
Watch: Numbers Game: How '108' Plays Into the Chicago Cubs' Historic World Series Run
