Pharrell Williams and Coldplay will also help raise money for the people affected by the attack.
Ariana Grande will appear on a Manchester stage two weeks after a suicide bombing turned her most recent concert into a scene of death and senseless violence.
A slew of other pop stars will appear alongside Grande to help raise money for the families of the 22 people killed in the May 22 blast, as well as the dozens of injured concertgoers.
Watch: Images Show Manchester Bomber Looking Calm Just Before Concert Blast
Among the luminaries appearing at the June 4 show will be Justin Bieber and Katy Perry.
Dubbed "One Love Manchester," the show will be held at Old Trafford cricket ground in Manchester, England's second largest city.
Proceeds will reportedly go to an emergency fund set up by the city of Manchester and the British Red Cross.
Like so many others, Grande's initial response was one of shock. However, the singer soon issued a statement of unity in the face of adversity.
"We won’t let this divide us," she said. "We won’t let hate win. Our response to this violence must be to come closer together, to help each other, to love more, to sing louder and to live more kindly and generously than we did before."
The June 4 concert will put her words into practice.
Watch: See Television Personalities' Emotional Reactions to Manchester Terror Bombing
Coldplay and singer Pharrell Williams will also appear at the event.
Ariana Grande fans who attended her concert at the Manchester Arena on Monday 22 May can register to attend One Love Manchester for free, according to the concert website.
Watch: Terror Experts Weigh In on Why Terrorists Target Concert Venues